Is berberine a viable alternative to Ozempic, a medication approved by the U.S. FDA for weight loss? TikTok users have coined the term “Nature’s Ozempic” while claiming that berberine can help you lose weight like Ozempic can. However, getting health advice from social media can be risky. It’s better to review the scientific evidence before concluding that berberine is an effective weight loss supplement. Berberine is a chemical compound found in plants like European barberry, goldenseal, and Oregon grape. Although it has been linked to various health benefits—from diabetes to polycystic ovary syndrome to weight loss—berberine has not received FDA approval as a treatment for any medical condition. Currently, it falls under dietary supplements, which do not undergo the same level of scrutiny as medications. While some laboratory and rat studies suggest that berberine can activate brown fat and possibly lead to weight loss, more high-quality studies are needed to determine its effectiveness in humans. The results of a meta-analysis of 49 trials conducted by Iranian researchers suggest that berberine use correlates with modest reductions in weight, body mass index, blood glucose, and cardiovascular risks. However, those studies had limitations such as small sample sizes and inadequate controls. Additionally, the analysis covered different purposes for which berberine was used, and the outcomes were broadly related to cardiovascular risk factors rather than weight loss. More studies are needed to determine how safe and effective berberine is over longer periods and to establish proper dosages. While using berberine is believed to have few side effects, people need to avoid it while breast-feeding infants due to the risk of bilirubin buildup in the newborn’s body, which can lead to brain damage. Ultimately, there isn’t enough scientific evidence to recommend berberine as “Nature’s Ozempic.”
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Jessica Irvine is a tech enthusiast specializing in gadgets. From smart home devices to cutting-edge electronics, Jessica explores the world of consumer tech, offering readers comprehensive reviews, hands-on experiences, and expert insights into the coolest and most innovative gadgets on the market.
