Home Science Potential Long Covid Risk Lowered by Taking Metformin Following Positive Test – Results of Clinical Trial

Potential Long Covid Risk Lowered by Taking Metformin Following Positive Test – Results of Clinical Trial

New research suggests that taking metformin, a medication commonly used to manage type 2 diabetes, soon after testing positive for COVID-19 may reduce the risk of developing long COVID by as much as 40% in overweight and obese individuals. The trial, involving 1,126 participants considered to be at higher risk of severe symptoms, found that 6.3% of those who took metformin within three days of testing positive reported a long COVID diagnosis within 10 months, compared with 10.4% who were given a placebo. The study is the first to suggest that medication taken at the earliest stages of COVID-19 may reduce the risk of long COVID. However, the trial did not investigate the effect of metformin on those already suffering from long COVID. The medication is generally considered safe, low-cost and widely accessible but is not suitable for those with a BMI under 25 or under 30 years of age. Some experts suggest that more research is needed, while others warn of potential gastrointestinal side effects and the importance of monitoring kidney function when taking metformin.

 

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