Mosquito-borne diseases, such as dengue and chikungunya, are serious global threats, infecting millions of people, particularly in Southeast Asia and Latin America. Bangladesh, like many other developing countries, faces frequent dengue outbreaks. This article critically examines the current status of dengue disease, traditional vector control approaches, and the potential for Wolbachia-mediated intervention in dengue-endemic developing countries.
The article draws upon a comprehensive search through major databases and search engines, including PubMed, BanglaJol, World Health Organization (WHO)/European Centre for Disease Prevention and Control (ECDC) and Google Scholar. After scrutinizing 55 related literature pieces based on several selection criteria, the article suggests that conventional vector control strategies are not entirely effective in preventing mosquito-borne diseases, and arbovirus disease burdens are rising. The lack of adequate outbreak preparedness, urbanization, climate change, and less efficacy of conventional approaches have left people vulnerable.
However, Wolbachia – a natural endosymbiont of many mosquito species that can potentially limit virus transmission through various host genetic modifications – is presented as a potential alternative for dengue prevention. The article also discusses the challenges and prospects of using Wolbachia-based methods and emphasizes the evidence backing its clinical efficacy and safety.
Empirical evidence suggests that the introgression method could serve as a sustainable and eco-friendly dengue control measure. Health policymakers and experts can utilize this review to develop effective strategies for Wolbachia-based dengue control to combat mosquito-borne diseases, particularly dengue, in developing countries like Bangladesh.
The research article is published in the journal, Biosafety and Health.
More information:
Abdullah Al Noman et al, Importance of Wolbachia-mediated biocontrol to reduce dengue in Bangladesh and other dengue-endemic developing countries, Biosafety and Health (2023). DOI: 10.1016/j.bsheal.2023.03.003
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Citation: Importance of Wolbachia-mediated biocontrol to reduce dengue in Bangladesh and other dengue-endemic developing countries (2023, June 9) retrieved 9 June 2023 from https://phys.org/news/2023-06-importance-wolbachia-mediated-biocontrol-dengue-bangladesh.html. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
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