Study suggests that brisk walking or gardening can offset genetic diabetes risk

Brisk walking, dancing, or gardening could reduce the risk of type 2 diabetes even in people with a high genetic risk of developing the condition, as per recent research. The study found that higher levels of total physical activity, particularly moderate to vigorous-intensity physical activity, were strongly associated with a lower risk of developing type 2 diabetes. The findings suggest physical exercise should be promoted as a major strategy for the prevention of type 2 diabetes, which affects almost four million people in the UK.

We are unable to control our genetic risk and family history, but this finding provides promising and positive news that through an active lifestyle, one can ‘fight off’ much of the excessive risk for type 2 diabetes

Associate Professor Melody Ding, University of Sydney

Associate Professor Melody Ding from the Faculty of Medicine and Health at the University of Sydney in Australia, the senior author, stated that although the role of genetics and physical activity in the onset of type 2 diabetes is well established, until now most data was self-reported, and little evidence was present as to whether the genetic risk could be counteracted by physical activity. She added that “We are unable to control our genetic risk and family history, but this finding provides promising and positive news that through an active lifestyle, one can ‘fight off’ much of the excessive risk for type 2 diabetes.”

Ms Ding said that moderate-intensity physical activity refers to movement that causes sweating and slight breathlessness, such as brisk walking and general gardening. Vigorous-intensity physical activities include running, aerobic dancing, cycling uphill or at a fast pace, and heavy gardening such as digging. These are activities that make you out of breath or cause you to breathe heavily.

The study involved 59,325 adults from the UK Biobank, a database containing genetic, lifestyle, and health information from half a million people, who wore accelerometers (activity trackers worn on their wrist) at the start of the study. They were then followed for up to seven years to track health outcomes. The data included information on genetic markers associated with a higher risk of developing type 2 diabetes. Researchers suggest that people with a high genetic risk score had 2.4 times the risk of developing type 2 diabetes when compared with those with a low genetic risk score.

The study found that doing over an hour of moderate to vigorous-intensity physical activity per day was associated with a 74% lower risk of developing type 2 diabetes when compared with people who did fewer than five minutes of physical activity. The research found that people with a high genetic risk, but who were in the most physically active category, had a lower risk of developing type 2 diabetes when compared with those with low genetic risk, but in the least active category. The findings are published in the British Journal of Sports Medicine.

Ms Ding, whose father was recently diagnosed with type 2 diabetes in his sixties, added: “My dad’s side of the family has a history of type 2 diabetes, so the result of the study is extremely heartening for my family and myself. As an already active person, I now have extra motivation to keep this active lifestyle. Our hope is that this study will inform public health and clinical guidelines so that it can help chronic disease prevention for health professionals, organizations, and the public.”

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