In the study, two different lipid droplets were used: oleic acid on the left and elaidic acid on the right. The Mediterranean diet, which is rich in healthy fats from nuts and olive oil, has been shown to lead to longer and healthier lives compared to diets filled with fast food and meat. While the cellular benefits of this diet have not been fully understood, scientists from Stanford School of Medicine have found that monounsaturated fatty acids, or healthy fats, are linked to longevity in laboratory worms. The researchers found that oleic acid, one of the fats found in the Mediterranean diet, increased the number of lipid droplets that protect cellular membranes from oxidation damage. These worms who were fed oleic acid lived about 35% longer than those fed with the standard worm rations. The researchers also discovered that the number of lipid droplets in individual worms can predict the remaining lifespan and that genetics can also play a role. While more research is necessary, the findings published in Nature Cell Biology suggest that there may be a fat-based strategy to improve human health and longevity.
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