Breakthroughs in nanosized contrast agents and drug carriers through self-folding molecules
By incorporating Gd-based contrast agents into a self-folding polymer, researchers from Tokyo Institute of Technology produced nanosized complexes where the motion of Gd ions is restricted. The small size of these complexes led to better accumulation in tumors, and the limited rotation and motion of Gd ions increased the MRI signal, leading to improved contrast. …